The Japanese Biochemical Society/The Molecular Biology Society of Japan

[3P-1122] In vivo analysis using model mice of dominantly inherited growth hormone deficiency ~A decrease in the Ghrhr mRNA contributes to the pathogenesis of GH deficiency in the model mice~

〇Daisuke Ariyasu1, Emika Kubo1, Shinsuke Shibata2, Kimi Araki1 (1.Dev. Genet., Ins. of Res. Dev. Analy, Univ of Kumamoto, 2.Elect. Microsco. Lab, Univ of Keio)

growth hormone deficiency、exon 3 skipping、dominant negative effect

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