The Japanese Biochemical Society/The Molecular Biology Society of Japan

5:14 PM - 5:37 PM

[3PW02-4] Simultaneous Single Nicking of Target Gene and Donor Plasmid Enables Safe and Efficient Gene Correction by Non-Canonical HDR.

LOD 【J】

Kazuhiro Nakajima1, Yue Zhou1, Akiko Tomita1, Yoshihiro Hirade1, 〇Shinichiro Nakada1,2 (1.Cell. Resp. Grad Sch. Med. Osaka Univ., 2.Inst, Co-Cre. Osaka Univ.)

gene correction、nucleotide substitution、homology directed repair、Crispr/Cas9、nickase

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