The Japanese Biochemical Society/The Molecular Biology Society of Japan

ConBio2017

ConBio2017

Dec 6, 2017 - Dec 9, 2017
Kobe Port Island(Kobe International Conference Center, Kobe Portopia Hotel, Kobe International Exhibition Hall, The Kobe Chamber of Commerce and Industry)

4:35 PM - 4:45 PM

[4P2T27-03（3P-1412）] Anti-CD26 humanized monoclonal antibody conjugated to triptolide is transported into nucleus and impairs RNA polymerase II

〇Taketo Yamada1,2, Hiroko Madokoro2, Hiroko Nishida2, Chikao Morimoto3, Michiie Sakamoto2, Mutsumi Hayashi2 (1.Dept. Pathol., Saitama Med. Univ., 2.Dept. Pathol., Keio Univ., 3.Dept. Therapy Dev. Innov. Immune, Juntendo Univ.)

antibody-drug conjugate、CD26、RNA polymerase II、nuclear transport、triptolide

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