[1P-1158] Impact of intracellular glyceraldehyde-derived advanced glycation end-products on human hepatocyte cell death

〇Akiko Sakasai-Sakai¹, Takanobu Takata¹, Masayoshi Takeuchi¹ (1.Med. Res. Inst., Kanazawa Med. Univ.)

ConBio2017

[1P-1159] Fibroblasts derived from patients of Werner syndrome exhibit cellular senescence due to WRN deficiency

〇Shuichi Shibuya^1,2, Kinue Iizuka¹, Koutaro Yokote¹, Takahiko Shimizu¹ (1.Chiba Univ. Grad. Sch. of Med., 2.JSPS Research Fellow DC1)

ConBio2017

[1P-1160] Analysis on the mechanism of DNA demethylation in the formation of solar lentigines

〇Takaaki Yamada^1,2,3, Seiji Hasegawa^1,3,4, Yu Inoue¹, Yoshie Ishii², Mika Kawagishi Hotta^1,2,4, Masaru Arima³, Yohei Iwata³, Naoki Yamamoto⁵, Satoru Nakata¹, Kazumitsu Sugiura³, Hirohiko Akamatsu² (1.Research Laboratories, NIPPON MENARD COSMETIC CO., LTD., 2.Department of Applied Cell and Regenerative Medicine, Fujita Health University School of Medicine, 3.Department of Dermatology, Fujita Health University School of Medicine, 4.Nagoya University-MENARD Collabprative Chair, Nagoya University Gradutae School of Medicine, 5.Laboratory of Molecular Biology and Histochemistry, Joint Research Support Promotion Facility, Center for Research Promotion and Support, Fujita Health University)

ConBio2017

[1P-1161] Time-restricted feeding during the inactive phase induces adipose tissue accumulation without adipocyte hypertrophy in mice.

〇Rei Kazama^1,2, Tomoki Abe¹, Katsutaka Oishi^1,2,3 (1.Biological Clock Res. Group, Biomedical Res. Inst., AIST, 2.Dept. of Computational Biol. and Med. Sci., Grad. Sch. of Frontier Sci., Univ. of Tokyo, 3.Dept. of Applied Biological Sci., Grad. Sch. of Sci. and Technol., Tokyo Univ. of Sci.)

ConBio2017

[1P-1162] Long-term influence of maternal diabetes on the phenotype and gene expression of the offspring in adulthood

〇Yukihiro Inoguchi¹, Kenji Ichiyanagi², Hiroaki Ohishi¹, Yasutaka Maeda⁴, Yoshihiro Ogawa^3,5,6, Toyoshi Inoguchi⁷, Hiroyuki Sasaki ¹ (1.Div. Epigenomics and Dev., Med. Inst. Bioreg., Kyushu Univ., 2.Grad. Sch. of Bioagricultual Sci., Nagoya Univ, 3.Grad. Sch. of Medical Sci., Dep. of Med. and Bioreg. Sci., Kyushu Univ., 4.Clinic Minami Masae, Diabetes Clinical Research Cent., 5.Grad. Sch. of Med. and Dent. Sci., Tokyo Medical and Dental Univ., 6.AMED-CREST, 7.FUKUOKA Health Promotion Support Cent.)

ConBio2017

[1P-1163] Loss of KLF14 impairs obesity-induced remodeling of white adipose tissue in mice

〇Chiharu Tayama¹, Rieko Takanashi², Junko Tomikawa¹, Hajime Okita³, Kenji Matsumoto⁴, Kenichiro Hata¹, Tadashi Okamura², Kazuhiko Nakabayashi¹ (1.Dept. of Mat.-Fetal Biol., NCCHD, 2.Dept. of Infectious Dis., Res. Inst., NCGM, 3.Dept. of Pathol. , Keio Univ. Sch. of Medicine , 4.Dept. of Allergy and Clinical immunol., NCCHD)

ConBio2017

[1P-1164] Immortalization of naked mole rat-derived dermal fibroblasts and genome editing

〇Maki Nakasone^1,2, Teruhiko Suzuki¹, Kyouko Miura³, Takahiko Hara^1,2 (1.Stem Cell Project, Tokyo Metropol. Inst. Med. Sci., 2.Grad. Sch., Tokyo Med. Dent. Univ., 3.Inst. Genet. Med., Hokkaido Univ.)

ConBio2017

[1P-1165] Establishment of new biomarkers for type 2 diabetes using T2DM model mice.

〇Mao Kawamura¹, Syoko Tsuchiya¹, Shun-ichiro Asahara², Yoshiaki Kido^1,2 (1.Div. of Med. Chem., Dept. of Bioph., Grad. Sch. of Hlth Sci., Univ. of Kobe, 2.Div. of Dia. and Endo., Grad. Sch. of Med., Univ. of Kobe)

ConBio2017

[1P-1166] Effects of anti-hypertensive drugs on maternal hemolysis in pregnancy-associated hypertensive mice

〇Misaki Nakashima¹, Gyokurei Sya², Junji Ishida³, Akiyoshi Fukamizu³ (1.Col. of Agro-Bio.Res. Sci., Univ. of Tsukuba, 2.Grad. Sch. of Life and Env. Sci., Univ. of Tsukuba, 3.Life Sci. Cent. of Tsukuba Adv. Res. Alliance, Univ. of Tsukuba)

ConBio2017

[1P-1168] Metabolomic analysis elucidate brain metabolic abnormalities associated with diabetes

〇Kumiko Sakai¹, Mami Sakurai¹, Seiichi Chiba² (1.Res. Prom. Inst., Fac. of Med., Oita Univ., 2.Mol. Anat., Fac. of Med., Oita Univ.)

ConBio2017