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[2P-172] Theoretical investigation on the free energy changes of reaction intermediates of threonine synthase

Ujiie Yuzuru1, Tanaka Wataru1, Shoji Mitsuo1, Kayanuma Megumi2, Shigeta Yasuteru1, Machida Yasuhiro3, Murakawa Takeshi4, Hayashi Hideyuki3 (1.Grad. Sch. of Pure & Appl. Sci., Univ. of Tsukuba, 2.Grad. Sch. of Sys. & Inf. Eng., Univ. of Tsukuba, 3.Dept. Chem., Osaka Medical College, 4.Dept. Biochem., Osaka Medical College)

分子動力学, 熱力学積分法, 自由エネルギー, 水素結合ネットワーク

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