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[2P-266] Combination with EGFR-TKI and specific inhibitors of the Ras/ERK pathway overcomes resistance to EGFR-TKI in NSCLC

Takeuchi Kenji1, Sakai Kazuki1, Doyama Mai1, Kobayashi Nao1, Ito Fumiaki2 (1.Dept. of Biochem., Fac. of Pharm. Sci., Setsunan Univ., 2.Institute of Health Sciences, Sunstar Inc.)

非小細胞肺がん, チロシンキナーゼ阻害剤, EGF, Bim, ERK

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