2:00 PM - 3:00 PM

[2P-299] Cystathionine β-synthase gene expression under hypoxia is regulated by hypoxia-inducible factors.

^○Takano Naoharu^1,2,3,4, Peng Ying-Jie⁵, Kumar Ganesh K.⁵, Luo Weibo^2,6, Hu Hongxia^2,3, Shimoda Larissa A.^7,8, Suematsu Makoto^1,4, Prabhakar Nanduri R.⁵, Semenza Gregg L.^{2,3,6,7,9,10,11} (1.JST ERATO Suematsu Gas Biology Project, 2.Inst. for Cell Engineering, Johns Hopkins Univ. School of Med., 3.McKusick-Nathans Inst. of Genetic Med., Johns Hopkins Univ. School of Med., 4.Dept. of Biochem., School of Med., Keio Univ., 5.Inst. for Integrative Physiology and Center for Systems Biology of O2 Sensing, Univ. of Chicago, 6.Dept. of Biological Chemistry, Johns Hopkins Univ. School of Med., 7.Dept. of Med., Johns Hopkins Univ. School of Med., 8.Div. of Pulmonary and Critical Care Med., Johns Hopkins Univ. School of Med., 9.Dept. of Pediatrics, Johns Hopkins Univ. School of Med., 10.Dept. of Oncology, Johns Hopkins Univ. School of Med., 11.Dept. of Radiation Oncology, Johns Hopkins Univ. School of Med.)

低酸素, 硫化水素, HIF, CBS