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[2P-461] (2T10p-09)Role of ESCRT machinery in the clearance of aggregate-prone proteins associated with neurodegenerative diseases

Hasegawa Takafumi1, Oosima Ryuji1,2, Takeda Atsushi3, Tanaka Nobuyuki1, Aoki Masashi1 (1.Div. of Neurol., Dep. of Neurosci. & Sens. Org., Tohoku Univ. Grad. Sch. of Med., 2.Div. of Cancer Biol. & Therapeut., Miyagi Cancer Cent. Res. Inst., 3.Sendai Nishitaga Hosp.)

ESCRT, neurodegenerative disease, protein degradation, autophagy, animal model

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