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[2P-466] Lipid-peroxidation stress induces oligomeization and insolubilization of alpha-synuclein, and modulate proteolysis system in SH-SY5Y cells

Shamoto-Nagai Masayo1, Hisaka Shinsuke2, Osawa Toshihiko3, Naoi Makoto3, Motoyama Noboru1, Manamiyama Makoto1, Maruyama Wakako1 (1.Dep. of Cognitive Brain Sci., NCGG, 2.Dept. of Pharmacognosy, Fac. of Pharm., Meijo Univ., 3.Dept. of Hlth. and Nutr. Fac. of Psycological & Physical Sci., Aichi Gakuin Univ.)

Oxidative stress, alpha-synuclein, Proteolysis System, cell death

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