The Japanese Biochemical Society

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[2S07a-6] Creation of novel anti-cancer drugs targeting NAD+-poly(ADP-ribose) metabolism

Tanuma Sei-ichi1, Abe Hideaki2, Oyama Takahiro2, Yoshimori Atsushi3, Sato Akira1, Uchiumi Fumiaki4, Masutani Mitsuko5 (1.Dep. of Biochm., Facul. of Pharm Sci.,Tokyo Univ. of Sci., 2.Hinoki Shinyaku Co.,Ltd., 3.Institute for Theoretical Medicine, Inc., 4.Dep. of Gene Regul., Facul. of Pharm Sci.,Tokyo Univ. of Sci., 5.Div. of Genome Stability Res. Natl. Cancer Center Res. Inst.)

poly(ADP-ribose), PARG, NAD+, apoptosis, anti-cancerdrug

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