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[3P-038] GTDC2 modifies O-mannosylated α-dystroglycan to generate N-acetyl-glucosamine epitopes reactive with CTD110.6 antibody

Ogawa Mitsutaka1,2, Sawaguchi Shogo1, Nakamura Naosuke3, Nakayama Yoshiaki3, Kurosaka Akira3, Manya Hiroshi4, Kanagawa Motoi5, Endo Tamao4, Furukawa Koichi1, Okajima Tetsuya1 (1.Sch. of Med., Nagoya Univ., 2.Dep. of Biosci., Nagahama Inst. of Bio-Sci. & Tech., 3.Dep. of Mol. Sci., Kyoto Sangyo Univ., 4.TMIG, 5.Sch. of Med., Kobe Univ.)

Dystroglycanopathy, O-GlcNAc, glycosylation, dystroglycan, ER

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