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[3P-131] (3T10p-04)Investigation of the amyloid fibril formation mechanism of SOD1 G93A mutant, a familial ALS causative protein and verification of the suppression of the amyloid fibril formation by polyphenol VMA

Ando Mizuho1, Ida Masataka1, Adachi Masayuki1, Hongo Kunihiro1, Mizobata Tomohiro1, Kobayashi Saori2, Yoshida Yamakawa Miho3, Watanabe Yasushiro3, Nakashima Kenji3, Kawata Yasushi1 (1.Dept. of Chem. & Biotech., Grad. Sch. of Eng., Tottori Univ., 2.Wakasa Seikatsu Corporation, 3.Dept. of Neurology, Faculty of Med., Tottori University)

SOD1, ALS, アミロイド線維, 神経変性病

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