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[4P-513] (4T15a-16)NCYM, a de novo gene evolved from MYCN antisense genes, encodes a protein regulating MYCN functions in human neuroblastomas

Suenaga Yusuke1,2, Shoji Wataru2,7, Rafiqul Islam2, Jennifer Alagu2, Yoshiki Kaneko2, Mamoru Kato3, Yukichi Tanaka4, Hidetada Kawana5, Shamim Hossain1, Makiko Itami5, Tatsuhiro Shibata3, Yohko Nakamura2, Miki Ohira6, Seiki Haraguchi2, Sana Yokoi1, Akira Nakagawara2,8 (1.Cancer Genome Ctr., Chiba Cancer Ctr. Res. Inst., 2.Div. Biochem. & Innov. Cancer Therap.,Chiba Cancer Ctr. Res. Inst., 3.Div. Cancer Genomics, Natl. Cancer Ctr. Res. Inst., 4.Dept. of Path., Kanagawa Children's Medical Ctr., 5.Div. Clin. Path., Chiba Cancer Ctr., 6.Div. Cancer Genomics, Chiba Cancer Ctr. Res. Inst., 7.Dept. of Pediatric Surgery, Grad. Sch. of Med., Tohoku Univ., 8.Saga Med. Ctr. Koseikan)

de novo gene, MYCN, NCYM, long non-coding RNA, neuroblastoma

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