8:37 AM - 8:55 AM

[4S08a-2] UBE3A, a E3 ubiquitin ligase that regulates the circadian clock in mammalian cells and flies

Meng Qing-Jun¹, Gossan Nicole¹, Guo Baoqiang¹, Zhang Feng¹, Yoshitane Hikari², Yao Aiyu³, Glossop Nick¹, Zhang Feng¹, Zhang Yong Q³, ^○Fukada Yoshitaka² (1.Faculty of Life Sciences, University of Manchester, UK, 2.Department of Biophysics and Biochemistry, Graduate School of Science, University of Tokyo, Tokyo 113-0033, Japan., 3.Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.)

Circadian clock, ubiquitination, oncogene, proteasomal degradation, BMAL1