The Japanese Biochemical Society

4:42 PM - 4:50 PM

[4T10p-10] (4P-122)A novel function of the kelch repeat protein KLHDC10 as a regulator of SMA-linked SMN through ubiquitin-mediated degradation

Yamaguchi Namiko1, Sekine Yusuke2, Sekine Shiori1, Ichijo Hidenori1 (1.Cell Signaling, Grad. Sch. Pharmaceut. Sci., Univ. of Tokyo, 2.Metabolic Research, NIHR Cambridge Biomedical Research Centre, Univ. of Cambridge)

SMN, cullin, ubiquitin, E3, neurodegenerative disease

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