Involvement of Nrf2 activation in the attenuation of cytocidal effects of arsenic trioxide against APL cells, via enhanced arsenic efflux associated with increment of GSH levels.

Shoichi Nishimoto

2:45 PM - 3:45 PM

[1P-034] Involvement of Nrf2 activation in the attenuation of cytocidal effects of arsenic trioxide against APL cells, via enhanced arsenic efflux associated with increment of GSH levels.

^○Shoichi Nishimoto¹, Shin Koike¹, Toshihiro Suzuki¹, Bo Yuan², Norio Takagi², Yuki Ogasawara¹ (1.Dept. of Anal. Biochem., Meiji Pharm Univ., 2.Dept. of Appl. Biochem., Tokyo Univ. of Pharm. & Life Sci.)

Nrf2, APL, 三酸化ヒ素, グルタチオン, MRP

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The 89th Annual Meeting of JBS

[1P-034] Involvement of Nrf2 activation in the attenuation of cytocidal effects of arsenic trioxide against APL cells, via enhanced arsenic efflux associated with increment of GSH levels.

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