The Japanese Biochemical Society

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[1P-226] Gamma-irradiated quiescent cells repair directly induced DSBs but accumulate persistent DSBs during subsequent DNA replication

Yusuke Minakawa1,2, Yuko Atsumi1, Akira Shinohara3, Yasufumi Murakami2, Ken-ichi Yoshioka1 (1.Division of Carcinogenesis and Cancer Prevention, National Cancer Center Research Institute., 2.Biological Science and Technology, Tokyo University of Science., 3.Division of Integrated Protein Functions, Institute for Protein Research, Osaka Univ.)

H2AX, γ-ray, DNA replication stress, senescence

yminagaw@ncc.go.jp

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