Conditional knockout of protein arginine methyltransferase 1 (PRMT1) in the central nervous system results in developmental defects and severe hypomyelination in mice.

Misuzu Hashimoto

1:30 PM - 2:45 PM

[1P-303] Conditional knockout of protein arginine methyltransferase 1 (PRMT1) in the central nervous system results in developmental defects and severe hypomyelination in mice.

^○Misuzu Hashimoto¹, Kazuya Murata², Junji Ishida², Akihiko Kanou³, Yoshitoshi Kasuya⁴, Akiyoshi Fukamizu^1,2,3 (1.Ph.D. Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, 2.Life Science Center, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, 3.Graduate School of Life and Environmental Sciences, University of Tsukuba, 4.Department of Biochemistry and Molecular Pharmacology, Graduate School of Medicine, Chiba University)

アルギニンメチル化, 髄鞘, オリゴデンドロサイト

mhashimoto@tara.tsukuba.ac.jp

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The 89th Annual Meeting of JBS

[1P-303] Conditional knockout of protein arginine methyltransferase 1 (PRMT1) in the central nervous system results in developmental defects and severe hypomyelination in mice.

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