The Japanese Biochemical Society

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[1P-316] Dynein dysfunction causes endosomal accumulation of APP via alteration in retromer trafficking.

Nobuyuki Kimura1, Eriko Samura2, Keiko Suzuki1, Sachi Okabayashi3, Nobuhiro Shimozawa4, Yasuhiro Yasutomi4 (1.Lab. Cell Biol. & Pathol., Dept. Alzheimer Dis., NCGG, 2.Dept. Neurol., The Univ. of Tokyo, 3.Corp. Prod. Res. Lab. Primates, 4.Tsukuba Primate Res. Center, NIBIOHN)

アルツハイマー病, エンドサイトーシス, レトロマー, 老化

kimura@ncgg.go.jp

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