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[2P-030(2T05-06)] Apoptotic cells trigger microbiota-independent Reg3β production that maintains tissue homeostasis of the intestine

Ryodai Shindo1,2, Masaki Ohmuraya3, Sachiko Komazawa1, Sanae Miyake1, Soh Yamazaki1, Takashi Nishina1, Hiroyuki Konishi4, Hiroshi Kiyama4, Tetsuo Mikami5, Kimi Araki3, Hiroyasu Nakano1,2 (1.Dept. of Biochem., Sch. of Med., Toho Univ., 2.Dept. of Immunol., Sch. of Med., Juntendo Univ., 3.IRDA., Kumamoto Univ., 4.Dept. of Funct Anat and Neurosci., Sch. of Med., Nagoya Univ., 5.Dept. of Pathol., Sch. of Med., Toho Univ.)

Reg3β, Apoptosis, Tissue homeostasis, cFLIPs, X chromosome inactivation

rshindou@juntendo.ac.jp

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