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[2P-125] Effect on the enzyme activity by mutation to the substrate binding site of geranylgeranylglyceryl phosphate synthase of archaeal lipid synthesis enzyme

Yoshinori Shibanuma1, Ken-ichi Miyazono2, Satoshi Akanuma3, Gota Kawai1, Masaru Tanokura2, Akihiko Yamagishi4, Naoki Nemoto1 (1.Dep. of Life and Env. Sci.,Chiba Institute of Technology, 2.University of Tokyo, 3.Waseda univ., Sch of Human, 4.Tokyo Univ. of Pharmacy and Life Sci)

アーキア, 脂質, 変異導入, 酵素活性, 進化

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