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[2P-301] IDH1/2 mutants producing D-2-HG have an effect on Bone and Cartilage Differentiation

Takeshi Kamakura1,2, Yonghui Jin1,2, Makoto Watanabe2, Takeshi Okamoto3, Hiroyuki Yoshitomi1,2,3, Junya Toguchida1,2,3 (1.Dept. of Tissue Regeneration, Inst. of Front. Med. Sci., Kyoto Univ., 2.Dept. of Cell Growth and Differentiation, CiRA, Kyoto Univ., 3.Dept. of Orthopaedic Surgery, Graduate School of Med, Kyoto Univ.)

がん, IDH, D-2-HG, 骨・軟骨分化, 代謝

tkama@frontier.kyoto-u.ac.jp

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