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[2P-320] Regional fluctuation in the functional consequence of LINE-1 insertion in the Mitf gene: The black spotting phenotype arisen from the Mitfmi-bw mouse lacking melanocytes

Kazuhisa Takeda1, Hiroki Hozumi1, Koji Ohba1,2, Hiroaki Yamamoto3, Shigeki Shibahara1 (1.Dept. of Mol. Biol. and Applied Physiol., Tohoku Univ. Sch. of medicine, 2.Dept. of Endocrinol. and Applied Medical Science, Tohoku Univ. Sch. of Medicine, 3.Faculty of Biosci., Nagahama Inst. of Bio-Science and Technol.)

pigmentation, differentiation, melanocyte, MITF, transcription factor

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