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[2T07-05(2P-327)] Development and characterization of dermatan-O-sulfotransferase1-deficient mice as Ehlers-Danlos syndrome model

Yuko Kasahara1,2, Nana Tsumita1, Chiaki Masuda1, Sonoko Shimada1, Shuji Mizumoto3, Yukiko Inoue4, Takayoshi Inoue4, Takahiro Yoshizawa5, Jun Nakayama6, Aki Takahashi7, Shin'ichi Takeda2, Tomoki Kosho7, Takashi Okada1 (1.Biochem. and Mol. Biol., Nippon Medical School, 2.Dep. of Mol.Ther., Nat. Inst. of Neuroscience, NCNP, 3.Faculty of Pharmacy, Dep. of Pharmacy. Meijo Univ., 4.Dep. of Biochem. and Cell. Biol., Nat. Inst. of Neuroscience, NCNP, 5.Res. Cent. of Supports to Advanced Science, Shinshu Univ., 6.Dep. of Mol. Pathol., Shinshu Univ. Graduate School of Medicine, 7.Dep. of Med. Genetics, Shinshu Univ. School of Medicine)

疾患モデルマウス, CRISPR Cas9

y-kasahara@nms.ac.jp

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