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[2T11-02(2P-152)] The role of paratope side chains of a VHH in the interaction with the antigen from viewpoints of thermodynamics and structure

Hiroko Tamura1, Hiroki Akiba2, Masato Kiyoshi2, Jose Caaveiro2, Kouhei Tsumoto2,3 (1.Dept. of Chem. Biotech., Sch. of Eng., Univ. of Tokyo, 2.Dept. of Bioeng., Sch. of Eng., Univ. of Tokyo, 3.Inst. of Med. Sci., Univ. of Tokyo)

VHH, 抗体, hot-spot 熱力学, 結晶構造

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