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[3P-098] One-shot LC-MS/MS analysis of post-translational modifications including oxidation,deamidation and isomerization of rat lens α- and β-crystallins induced by γ-irradiation

Ingu Kim1, Takeshi Saito1,4, Norihiko Fujii2, Takashi Kanamoto3, Noriko Fujii1,4 (1.Res.Res.Inst.,Kyoto Univ., 2.Rad. Res. Ctr., Teikyo Univ., 3.Dept. of Oph., Hirosima Univ., 4.Dept. of Chem., Grad. Sch. of Sci., kyoto Univ.)

Amino acid, Gamma-irradiation, Oxidation, Crysatllin, Deamidation

in9-kou@rri.kyoto-u.ac.jp

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