Time-resolved XFEL crystallography revealed that the water channel closure is triggered by a ligand binding to the copper ion at binuclear center in cytochrome <I>c</I> oxidase

Atsuhiro Shimada

2:25 PM - 3:25 PM

[3P-143] Time-resolved XFEL crystallography revealed that the water channel closure is triggered by a ligand binding to the copper ion at binuclear center in cytochrome c oxidase

^○Atsuhiro Shimada¹, Keita Hatano¹, Akari Miyamoto¹, Kyoko Shinzawa-Itoh¹, Minoru Kubo⁴, Seiki Baba³, Takashi Kumasaka³, Masaki Yamamoto⁴, Hideo Ago⁴, Kunio Hirata⁴, Keitaro Yamashita⁴, Eiki Yamashita⁴, Go Ueno⁴, Shinya Yoshikawa¹, Tomitake Tsukihara^1,2 (1.Picobiol. Inst., Grad. Sch. Life Sci., Univ. Hyogo, 2.Inst. Protein Res., Osaka Univ., 3.JASRI, 4.RIKEN, SPring-8)

チトクロム酸化酵素, X線自由電子レーザー, プロトンポンプ, 時分割構造解析, 膜蛋白質

ashima@sci.u-hyogo.ac.jp

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The 89th Annual Meeting of JBS

[3P-143] Time-resolved XFEL crystallography revealed that the water channel closure is triggered by a ligand binding to the copper ion at binuclear center in cytochrome c oxidase

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