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[3P-293] Quantitative analysis of p53 hetero-tetramers between wild-type and mutant in transcriptional activity by single living cell reporter assay

Yu Toguchi1,2, Madoka Kanno1, Rui Kamada1,2, Toshiaki Imagawa1,2, Kazuyasu Sakaguchi1,2 (1.Lab. of Biol. Chem., Grad. Sch. of Chem. Sci. & Eng. Hokkaido Univ., 2.Lab. of Biol. Chem., Dept. of Chem., Fac. of Sci., Hokkaido Univ.)

Tumor suppressor protein p53, Dominant-negative effect, Mutation, Hetero-oligomerization, Single living cell

yu23@mail.sci.hokudai.ac.jp

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