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[3P-309(3T06-05)] Acrolein conjugation activates matrix metalloproteinase 9 in the saliva of primary Sjogren's syndrome patients

Takeshi Uemura1, Takehiro Suzuki2, Ryotaro Saiki1,3, Tadao Hirose3, Naoshi Dohmae2, Satoshi Ito4,5, Hoyu Takahashi5, Itsuko Ishii3, Toshihiko Toida3, Keiko Kashiwagi6, Kazuei Igarashi1,3 (1.AminePharma Res. Inst., 2.RIKEN, 3.Grad. Sch. Pharm. Sci., Chiba Univ., 4.Dept. of Rheumato., Niigata Rheumatic Center, 5.Niigata Prefec. Kamo Hosp., 6.Fac. of Pharm., Chiba Inst. of Sci.)

アクロレイン, MMP-9, 原発性シェーグレン症候群

uemura@amine-pharma.com

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