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[3P-335(3T17-03)] Comparison of mode of action and molecular target of covalent-binding anti-cancer compounds isolated from fungi

Shota Uesugi1, Makoto Muroi2, Yasumitsu Kondoh2, Tetsuro Yamashita1, Yoshihito Shiono3, Masaru Hashimoto4, Hiroyuki Osada2, Ken-ichi Kimura1 (1.The Unit. Grad. Sch of Agri. Sci., Iwate Univ., 2.CSRS, RIKEN, 3.Fac. of Agri., Yamagata Univ., 4.Fac. of Agri. and Life Sci., Hirosaki Univ.)

covalent-binding drug, kinase, Keap1-Nrf2, proteasome

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