[1P-039] 骨異形成性老人性皮膚症のモデルマウス(Gorab欠損マウス)はデルマタン硫酸が低下する

Wing Lee Chan^1,2,3, Magdalena Steiner^1,4, Tomasz Witkos⁵, Johannes Egerer¹, Bjorn Busse⁶, ^○水本 秀二^7,8, Jan M. Pestka⁶, Haikuo Zhang¹, Ingrid Hausser⁹, Layal Abo Khayal¹, Claus-Eric Ott¹, Mateusz Kolanczyk², Bettina Willie⁴, Thorsten Schinke⁶, Chiara Paganini¹⁰, Antonio Rossi¹⁰, 菅原 一幸⁷, Michael Amling⁶, Petra Knaus¹¹, Danny Chan³, Martin Lowe⁵, Stefan Mundlos^1,2, Uwe Kornak^1,2 (1.Institut fur Medizinische Genetik und Humangenetik, Charite, Germany, 2.Max-Planck-Institut fuer Molekulare Genetik, Germany, 3.The University of Hong Kong, China, 4.Charite - Universitatsmedizin, Germany, 5.University of Manchester, United Kingdom, 6.University Medical Center Hamburg-Eppendorf, Germany, 7.北大院・生命, 8.名城大・薬, 9.University Clinic Heidelberg, Germany, 10.University of Pavia, Italy, 11.Freie Universitat, Germany)

キーテクノロジー：HPLC

ゴルジン、GORAB、デルマタン硫酸、コンドロイチン硫酸、骨・皮膚疾患