[1P-039] A mouse model for gerodermia osteodysplastica, Gorab-null mice, shows a reduction in dermatan sulfate

Chan Wing Lee^1,2,3, Steiner Magdalena^1,4, Witkos Tomasz⁵, Egerer Johannes¹, Busse Bjorn⁶, ^○Mizumoto Shuji^7,8, Pestka Jan M.⁶, Zhang Haikuo¹, Hausser Ingrid⁹, Khayal Layal Abo¹, Ott Claus-Eric¹, Kolanczyk Mateusz², Willie Bettina⁴, Schinke Thorsten⁶, Paganini Chiara¹⁰, Rossi Antonio¹⁰, Sugahara Kazuyuki⁷, Amling Michael⁶, Knaus Petra¹¹, Chan Danny³, Lowe Martin⁵, Mundlos Stefan^1,2, Kornak Uwe^1,2 (1.Institut fur Medizinische Genetik und Humangenetik, Charite, Germany, 2.Max-Planck-Institut fuer Molekulare Genetik, Germany, 3.The University of Hong Kong, China, 4.Charite - Universitatsmedizin, Germany, 5.University of Manchester, United Kingdom, 6.University Medical Center Hamburg-Eppendorf, Germany, 7.Hokkaido University, Japan, 8.Meijo University, Japan, 9.University Clinic Heidelberg, Germany, 10.University of Pavia, Italy, 11.Freie Universitat, Germany)

キーテクノロジー：HPLC

ゴルジン、GORAB、デルマタン硫酸、コンドロイチン硫酸、骨・皮膚疾患