[1P-123] Crystal Structure of Human Hydroxymethylbilane Synthase in Complex with Two Substrate Molecules

^○Sato Hideaki¹, Sugishima Masakazu¹, Tsukaguchi Mai¹, Masuko Takahiro², Omata Yoshiaki³, Wada Kei⁴, Hisaeda Yoshio², Yamamoto Ken¹ (1.Dept. of Med. Biochem., Kurume Univ. Sch. of Med., 2.Grad. Sch. of Eng., Kyushu Univ., 3.Fac. of Phar. Sci., Yokohama Univ. of Phar., 4.Dept. of Med. Sci., Univ. of Miyazaki)

キーテクノロジー：X線結晶構造解析　　

テトラピロール生合成、ヘム生合成、ジピロメタン補因子、ポルホビリノーゲンデアミナーゼ