Inhibition of intestinal tumorigenicity in mice lacking TMEPAI gene involved in a negative feedback loop of TGF-&beta; signaling

Shibasaki Teppei

[1P-281] Inhibition of intestinal tumorigenicity in mice lacking TMEPAI gene involved in a negative feedback loop of TGF-β signaling

^○Shibasaki Teppei¹, Sano Keigo¹, Sawada Yutaro¹, Amano Syoei¹, Ishikawa Ryo¹, Ito Fumiko², Watanabe Yukihide³, Taketo Makoto M⁴, Kato Mitsuyasu³, Ito Susumu¹ (1.Laboratory of Biochemistry, Showa Pharmaceutical University, 2.Laboratory of Cardiovascular Medicine, Tokyo University of Pharmacy and Life Sciences, 3.Department of Experimental Pathology, Faculty of Medicine, University of Tsukuba, 4.Department of Pharmacology, Graduate School of Medicine, Kyoto University)

キーテクノロジー：ノックアウトマウス

TGF-β、TMEPAI、Apc

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The 91th Annual Meeting of JBS

[1P-281] Inhibition of intestinal tumorigenicity in mice lacking TMEPAI gene involved in a negative feedback loop of TGF-β signaling

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