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[1T12a-03(1P-127)] Biochemical and structural characterizations of a non-canonical isocitrate dehydrogenase with activity towards NADP and NAD localized in Trypanosoma brucei

Wang Xinying1,2, Inaoka Daniel Ken1,2,3, Balogun Emmanuel O1, Ziebart Nicole4, Allmann Stefan5, Boshart Michael4, Bringaud Frederic5, Shiba Tomoo6, Harada Shigeharu6, Kita Kiyoshi1,2,3 (1.Dept. of Biomedical Chemistry, Graduate School of Medicine, Univ. Tokyo, 2.School of Tropical Medicine and Global Health, Univ. Nagasaki, 3.Dept. of Host-Defense Biochemistry, Institute of Tropical Medicine, Univ. Nagasaki, 4.Biocenter, Genetics, Ludwig Maximilians Univ. Munich, 5.Magnetic Resonance Center of Biological Systems, Univ. Bordeaux, 6.Dept. of Applied Biology, Kyoto Institute of Technology)

キーテクノロジー:enzyme characterization and crystallography

isocitrate dehydrogenase 、coenzyme specificity、trypanosome、metabolism、glycosome

wangxinying1229@gmail.com

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