1:09 PM - 1:21 PM

[1T12a-03(1P-127)] Biochemical and structural characterizations of a non-canonical isocitrate dehydrogenase with activity towards NADP and NAD localized in Trypanosoma brucei

^○Wang Xinying^1,2, Inaoka Daniel Ken^1,2,3, Balogun Emmanuel O¹, Ziebart Nicole⁴, Allmann Stefan⁵, Boshart Michael⁴, Bringaud Frederic⁵, Shiba Tomoo⁶, Harada Shigeharu⁶, Kita Kiyoshi^1,2,3 (1.Dept. of Biomedical Chemistry, Graduate School of Medicine, Univ. Tokyo, 2.School of Tropical Medicine and Global Health, Univ. Nagasaki, 3.Dept. of Host-Defense Biochemistry, Institute of Tropical Medicine, Univ. Nagasaki, 4.Biocenter, Genetics, Ludwig Maximilians Univ. Munich, 5.Magnetic Resonance Center of Biological Systems, Univ. Bordeaux, 6.Dept. of Applied Biology, Kyoto Institute of Technology)

キーテクノロジー：enzyme characterization and crystallography

isocitrate dehydrogenase 、coenzyme specificity、trypanosome、metabolism、glycosome