[2P-017(2T12m-08)] Lysoglycosphingolipids induce neuronal cell death by inhibition PI3K/Akt signaling

^○Watanabe Ryosuke¹, Tsuji Daisuke^1,2, Tanaka Hiroki², Uno Shintaro M.², Ohnishi Yukiya², Yamamoto Kei³, Hirokawa Takatsugu⁴, Okino Nozomu⁵, Ito Makoto⁵, Itoh Kohji^1,2 (1.Department of Medicinal Biotechnology, Faculty of Pharmaceutical Science, Tokushima University, 2.Department of Medicinal Biotechnology, Graduate school of Pharmaceutical Science, Tokushima University, 3.Graduate School of Bioscience and Bioindustry, Tokushima University, 4.Molecular Profiling Research Center for Drug Discovery (molprof), National Institute of Advanced Industrial Science and Technology (AIST), 5.The Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University)

キーテクノロジー：抗原抗体反応

PI3K/Akt、スフィンゴ糖脂質、神経細胞死