A novel mechanism of inhibition of CaM kinase phosphatase (CaMKP): Specific carbonylation of CaMKP by pyrogallol derivatives

Ishikawa Shun

[2P-200] A novel mechanism of inhibition of CaM kinase phosphatase (CaMKP): Specific carbonylation of CaMKP by pyrogallol derivatives

^○Ishikawa Shun¹, Obatake Rika¹, Ozaki Hana¹, Shimoda Nao¹, Nehira Tatsuo¹, Yamazaki Takeshi¹, Kinumi Tomoya², Kameshita Isamu³, Sueyoshi Noriyuki³, Shigeri Yasushi^4,5, Ishida Atsuhiko¹ (1.Grad. Sch. Integr. Arts Sci., Hiroshima Univ., 2.NIMIJ, AIST,, 3.Dept. Appl. Biol. Sci., Fac. Agr., Kagawa Univ., 4.Health Res. Inst., AIST, 5.Dept. Chem., Wakayama Med. Univ.)

キーテクノロジー：Phosphatase assay

プロテインホスファターゼ、カルボニル化、阻害剤、スクリーニング

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The 91th Annual Meeting of JBS

[2P-200] A novel mechanism of inhibition of CaM kinase phosphatase (CaMKP): Specific carbonylation of CaMKP by pyrogallol derivatives

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