[2P-283] Suppression of tumorigenicity for mesothelioma: a novel approach to inhibit function of YAP

^○Nakano Naoko¹, Kawamoto Rie¹, Ishikawa Ryo¹, Sano Keigo¹, Fukuda Kazuo², Shouda Takuji³, Hattori Takayuki⁴, Kurihara Masaaki³, Yamazaki Ryu², Nakane Takahisa⁵, Okamoto Iwao², Naito Mikihiko⁴, Itoh Susumu¹ (1.Laboratory of Biochemistry, Showa Pharmaceutical University, 2.Laboratory of Pharmaceutical Organic Chemistry, Showa Pharmaceutical University, 3.Division of Organic Chemistry, National Institute of Health Sciences, 4.Division of Molecular Target and Gene Therapy Products, National Institute of Health Sciences, 5.Laboratory of Natural Products Chemistry, Showa Pharmaceutical University)

キーテクノロジー：分子細胞生物学

TMEPAIファミリー、YAP、SNIPER、プロテインノックダウン法