[2P-310(2T14a-10)] Mice with an Oncogenic HRAS Mutation are Resistant to High-Fat Diet-Induced Obesity and Exhibit Impaired Hepatic Energy Homeostasis

^○Inoue Shinichi¹, Oba Daiju², Miyagawa-Tomita Sachiko³, Nakashima Yasumi⁴, Niihori Tetsuya¹, Yamaguchi Seiji⁵, Matsubara Yoichi^1,6, Aoki Yoko¹ (1.Dept. of Med. Genetics, Tohoku Univ. Grad. Sch. of Med., 2.Div. of Med. Genetics, Saitama Child. Med. Center, 3.Dept. of Veterinary Technology, Yamazaki gakuen Univ., 4.Dept. of Pediatrics, Seirei Hamamatsu General Hosp., 5.Dept. of Pediatrics, Shimane Univ., Faculty of Med., 6.Nat. Res. Ins. for Child Health Dep.)

キーテクノロジー：タンデムマス・スクリーニング

HRAS、RASopathies、コステロ症候群、ミトコンドリアβ酸化、RAS/MAPK