The Japanese Biochemical Society

[2P-310(2T14a-10)] Mice with an Oncogenic HRAS Mutation are Resistant to High-Fat Diet-Induced Obesity and Exhibit Impaired Hepatic Energy Homeostasis

Inoue Shinichi1, Oba Daiju2, Miyagawa-Tomita Sachiko3, Nakashima Yasumi4, Niihori Tetsuya1, Yamaguchi Seiji5, Matsubara Yoichi1,6, Aoki Yoko1 (1.Dept. of Med. Genetics, Tohoku Univ. Grad. Sch. of Med., 2.Div. of Med. Genetics, Saitama Child. Med. Center, 3.Dept. of Veterinary Technology, Yamazaki gakuen Univ., 4.Dept. of Pediatrics, Seirei Hamamatsu General Hosp., 5.Dept. of Pediatrics, Shimane Univ., Faculty of Med., 6.Nat. Res. Ins. for Child Health Dep.)

キーテクノロジー:タンデムマス・スクリーニング

HRAS、RASopathies、コステロ症候群、ミトコンドリアβ酸化、RAS/MAPK

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