Galactose on α-1,6-mannose branch of Fc glycan attached to therapeutic antibody plays a critical role for complement dependent cytotoxicity.

Hashii Noritaka

[2P-354] Galactose on α-1,6-mannose branch of Fc glycan attached to therapeutic antibody plays a critical role for complement dependent cytotoxicity.

Hashii Noritaka¹, Tsukimura Wataru², ^○Aoyama Michihiko¹, Osumi Kenji², Kiyoshi Masato¹, Tada Minoru¹, Matsuda Akio², Ishii Akiko¹ (1.National Institute of Health Sciences, 2.The Noguchi Institute)

キーテクノロジー：糖鎖挿げ替え技術

抗体医薬品、糖鎖均一化、補体依存性細胞傷害活性

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The 91th Annual Meeting of JBS

[2P-354] Galactose on α-1,6-mannose branch of Fc glycan attached to therapeutic antibody plays a critical role for complement dependent cytotoxicity.

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