The Japanese Biochemical Society

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[2S09m-04] BMP/Smad pathway of pre-osteoblast is suppressed by multiple myeloma-derived exosomes via inhibition of DNA binding Smad

Ikuo Mariko1,2, Sugisaki Kei2, Teramachi Jumpei3, Tahara Hidetoshi1, Abe Masahiro4, Itoh Kohji2 (1.Cellular and Molecular Biology, Graduate School of Biomedical Sciences, Hiroshima University, 2.Department of Medicinal Biotechnology, Institute of Biomedical Sciences, Graduate School of Pharmaceutical Sciences, Tokushima University, 3.Department of Tissue Regeneration, Institute of Biomedical Sciences, Tokushima University Graduate School, 4.Department of Hematology, Endocrinology and Metabolism, Institute of Biomedical Sciences, Tokushima University Graduate School)

キーテクノロジー:reporter assay

BMP、Smad、exosome

ikuo@hiroshima-u.ac.jp

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