The Japanese Biochemical Society

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[2T12e-05(2P-183)] Novel inhibitor of HMGB1-inducecd inflammatory response using in silico approach and its action mechanism

Tamada Kenya1,2, Nakajima Shingo1, Yoshimori Atsushi3, Sato Akira1, Takasawa Ryoko2, Tanuma Sei-ichi1,4 (1.Dept. Biochem., Fac. Pharm. Sci., Tokyo Univ. Sci., 2.Dept. Med. Mol. Biol., Fac. Pharm. Sci., Tokyo Univ. Sci., 3.Institute for Theoretical Medicine, Inc., 4.Lab. Genomic Med. Sci., Res. Inst. Sci. & Tech., Org. Res. Adv., Tokyo Univ. Sci.)

キーテクノロジー:in silico創薬

HMGB1、RAGE、TLR、sepsis、inflammation

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