Phosphorylation of RNF43 is an essential switch to suppress Wnt signalling and regulates embryonic development, stem cell maintenance and tumorigenesis.

Tsukiyama Tadasuke

6:24 PM - 6:36 PM

[2T12e-08(2P-190)] Phosphorylation of RNF43 is an essential switch to suppress Wnt signalling and regulates embryonic development, stem cell maintenance and tumorigenesis.

^○Tsukiyama Tadasuke¹, Terai Sayuri¹, Takahashi Hidehisa², Ishitani Tohru³, Koo Bon-Kyoung⁴, Hatakeyama Shigetsugu¹ (1.Hokkaido University Faculty of Medicine and Graduate School of Medicine, Department of Biochemistry, 2.Yokohama City University Graduate School of Medical Science, Department of Molecular Biology, 3.Gunma University, Institute for Molecular and Cellular Regulation, Laboratory of Integrated Signaling Systems, 4.Institute of Molecular Biotechnology, Austria)

キーテクノロジー：organoid assay

Wnt、RNF43、tumorigenesis、stem cell、homeositasis

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The 91th Annual Meeting of JBS

[2T12e-08(2P-190)] Phosphorylation of RNF43 is an essential switch to suppress Wnt signalling and regulates embryonic development, stem cell maintenance and tumorigenesis.

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