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[2T14m-03(2P-256)] Single cell analysis of necroptosis execution by FRET biosensor

Murai Shin1, Yamaguchi Yoshifumi2, Shirasaki Yoshitaka3, Shindo Ryodai1, Nakabayashi Osamu1, Joanne Hildebrand4, Tomida Taichiro5, Akahane Satomi5, John Silke4, Miura Masayuki6, Nkano Hiroyasu1,7 (1.Division of Medical Chemistry, Department of Biochemistry, Faculty of Medicine, Toho University, 2.Hibernation Metabolism, Physiology, and Development Group, ILTS, Hokkaido University, 3.Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 4.WEHI, University of Melbourne, 5.Department of Physiology, School of Medicine, Faculty of Medicine, Toho University, 6.Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7.Toho University Host Defence Reaseach Center)

キーテクノロジー:1分子FRET

ネクロプトーシス、プログラム細胞死、RIPK3、MLKL、FRET

mryshin@med.toho-u.ac.jp

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