Heterogeneity of ganglioside GM3S regulated by tumor hypoxia contributes to therapy-resistance of melanoma.

Shimizu Takuto

[3P-044] Heterogeneity of ganglioside GM3S regulated by tumor hypoxia contributes to therapy-resistance of melanoma.

^○Shimizu Takuto¹, Nagane Masaki¹, Murata Takuma¹, Kawashima Nagako², Maruo Takuya³, Yoshioka Chie³, Yamashita Tadashi¹ (1.Laboratory of Biochemistry, School of Veterinary Medicine, Azabu University, 2.Department of Nephrology, Kitasato University School of Medicine, 3.Teaching Animal Hospital, Azabu University)

キーテクノロジー：CRISPAR/CAS9

スフィンゴ糖脂質、ガングリオシドGM3合成酵素、腫瘍内低酸素領域、酸化ストレス、がん治療抵抗性

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The 91th Annual Meeting of JBS

[3P-044] Heterogeneity of ganglioside GM3S regulated by tumor hypoxia contributes to therapy-resistance of melanoma.

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