[3P-105(3T11m-08)] Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II

^○Osaki Yosuke¹, Saito Atsushi², Orii Kenji³, Fukao Toshiyuki³, Tomatsu Shunji^3,4, Imaizumi Kazunori¹ (1.Department of Biochemistry, Institute of Biomedical & Health Sciences, Hiroshima University, 2.Department of Stress Protein Processing, Institute of Biomedical & Health Sciences, Hiroshima University, 3.Department of Pediatrics, Graduate School of Medicine, Gifu University, 4.Department of Biological Sciences, University of Delaware)

キーテクノロジー：免疫染色

IDS、ERAD、ムコ多糖症II型