[1P-070] Evaluation of new potential mTOR inhibitors via in silico and in vitro hybrid selections

^○Raef Shams^1,2, Hideyuki Miyatake^2,3, Yoshihiro Ito^1,3 (1.Emergent Bioengineering Materials Research Team, RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan, 2.Department of Life Science, Graduate School of Science and Engineering, Saitama University, 255 Shimo-Okubo, Sakura-ku, Saitama-city, Saitama 338-8570, Japan, 3.Nano Medical Engineering Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan)

キーテクノロジー：Drug discovery

mTOR、Allosteric Inhibitors、Rapamycin、Virtual Ligand Screening、Protein-Protein interaction