[1P-099] Identification of Plasmodium falciparum mitochondrial malate:quinone oxidoreductase and dihydroorotate dehydrogenase inhibitors as antimalarial drug candidate

^○Endah D Hartuti¹, Takaya Sakura^2,3, Xinying Wang³, Kota Mochizuki¹, Rajib Archarjee¹, Yuichi Matsuo⁴, Tomoyoshi Nozaki⁵, Shinjiro Hamano⁶, Kiyoshi Kita^3,4,5, Daniel K Inaoka^2,3,5 (1.Grad School of Biomedical Science, Nagasaki University, 2.Dept of Molecular Infection Dynamics, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 3.School of Tropical Medicine and Global Health, Nagasaki University, 4.Dept of Host-Defense Biochemistry, NEKKEN, Nagasaki University, 5.Dept of Biomedical Chemistry, Grad School of Medicine, The University of Tokyo, 6.Dept of Parasitology, NEKKEN, Nagasaki University)

キーテクノロジー：inhibitor screening

Plasmodium falciparum、mitochondrial ETC、MQO、DHODH、HTS